FAQ - Frequently asked Questions

We are going to move to another town. Can our child still participate in the follow-up study?

It is not necessary to discontinue follow-up because of moving. If the distance between the new place of residence and the DIPP/TEDDY clinic is too long, it is possible to continue follow-up in one of the other two research units. The blood samples may also be arranged to be taken in the nearest primary health care unit.

 

Our child participates in two different follow-up studies. Is it possible to take the blood samples together to reduce the number of laboratory visits?

In most cases, it is possible to take blood samples for another study projects within Turku University Hospital at the DIPP/TEDDY clinic. On the other hand, the samples for DIPP/TEDDY study may be taken elsewhere if arranged well beforehand.

 

Our child has a sibling whose risk to develop type 1 diabetes has not been examined. Is it possible to perform the genetic screening to him/her?

The siblings of children in DIPP/TEDDY study may be screened for T1D risk genes if it has not been done before. They are also eligible for follow-up in case they have the genetic risk for T1D. The siblings may come to control visits together even if they participate in different studies (e.g. one in DIPP and one in TEDDY).

 

Is it painful to the child to take a blood sample?

In the DIPP/TEDDY/TrialNet Study, topical anesthetic is always used for children before taking a blood sample. It numbs the skin and makes the procedure painless. A small amount of EMLA cream is applied to both bends of the elbows, covered with an occlusive dressing and left in place at least one hour prior to procedure. The cream and the dressings for the purpose will be supplied to the parents beforehand. Small babies often cry when the blood sample is taken, because they do not like to sit still. This does not mean that they feel pain during the procedure.

Our child is antibody positive, should we restrict his/her sugar intake?

To date, dietary interventions have not been of use in preventing type 1 diabetes. On the other hand, less than a half of the antibody-positive children eventually develop diabetes. Dietary restrictions are therefore unnecessary.

 

What is a glucose tolerance test and why is it performed?

A glucose tolerance test is performed to the participants of the studies who have diabetes-related antibodies. Glucose tolerance test gives us information about the ability of the pancreas to produce insulin in response to elevated blood glucose levels. The child is given sugary solution to drink (oral glucose tolerance test) or intravenously (intravenous glucose tolerance test). Blood samples are taken for analysis of blood sugar and insulin concentrations before and after the glucose load. To avoid multiple punctures, blood samples are taken via a plastic cannula which is inserted into a vein in the arm of the child before the test.


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